THE ACUTE ABDOMENWord文件下载.docx
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THE ACUTE ABDOMENWord文件下载.docx
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Ifsurgerycarriednoriskanddidnotadverselyaffectthecourseofsomediseases,itwouldbesafetosay"
ifindoubt,operate."
Unfortunately,laparotomyitselfcarriesrisksandthecourseofsomedisorderssuchasacutepancreatitisandparalyticileusisadverselyinfluencedbyanesthesiaandsurgery.
Thediagnosisofacuteconditions,therefore,frequentlyresolvesitselfintoarrivingatafairlyimmediatejudgementderivedfromanaccurateanddetailedhistory,acarefulphysicalexaminationandafewselectedlabtestsandx-raystudies.Whilegatheringtheevidence,changesshouldbeevaluatedintermsofpathophysiologicalterationsratherthanspecificdiagnoses,andattentionmustbegiventotheneedforsupportivemeasureswhileinvestigationisunderway.
AnApproachtotheAcuteAbdomen
Oncompletionofthisminicourseyouwillbeableto:
1.Definetheacuteabdomen.
2.Describethecauseandpathophysiologyofthefollowingacuteabdominaldiseases:
oa.acuteappendicitis-inflammatory
ob.acutesmallbowelobstruction-mechanical
oc.mesentericvascularocclusionvascular
od.perforatedduodenalulcerperforatedviscus
oe.peritonitis
3.Identifyanddescribethesymptoms,signs,clinicalcourseandlaboratoryandx-rayfindingsfortheacuteabdominaldiseaseslistedunderObjective2.
4.Identifytheclinicalfeaturesthathelptodistinguishthesurgicalfromthenon-surgicalacuteabdomen.
5.Constructanapproachtoevaluationandmanagementoftheacuteabdomen.
MINICOURSE2.4SECTION1
OBJ.1.Definetheacuteabdomen.
DefinitionoftheAcuteAbdomen
Theacuteabdomenmaybedefinedgenerallyasanintraabdominalprocesscausingseverepainandoftenrequiringsurgicalintervention.Itisaconditionthatrequiresafairlyimmediatejudgementordecisionastomanagement.Generalcausesoftheacuteabdomenmaybedividedintosixlargecategories:
∙a.inflammatory
∙b.mechanical
∙c.neoplastic新生物
∙d.vascular
∙e.congenitaldefects先天缺陷
∙f.traumatic
Eachofthesecategorieshasmanytypicalexamples,ofwhichonlyafewofthemorecommonconditionswillbediscussedinthisminicourse.
Theinflammatorycategoryofcausesmaybedividedintotwosubgroups:
1)bacterial,and2)chemical.Somecommonexamplesofthebacterialcauseswouldincludeacuteappendicitis,diverticulitis,andsomecasesofpelvicinflammatorydisease.Anexampleofachemicalcausewouldbeaperforationofapepticulcer,wherespillageofacidgastriccontentscausesanintenseperitonealreaction.
Mechanicalcausesofanacuteabdomenincludesuchobstructiveconditionsasincarceratedhernia,post-operativeadhesions,intussusception,malrotationofthegutwithvolvulus,congenitalatresiaorstenosisofthegut.Themostcommoncauseoflargebowelmechanicalobstructioniscarcinomaofthecolon.
Vascularentitiesproducinganacuteabdomenincludemesentericarterialthrombosisorembolism.Whenthebloodsupplyiscutoff,necrosisoftissueresults,withgangreneofthebowel.
Congenitaldefectscanproduceanacuteabdominalsurgicalemergencyanytimefromtheminuteofbirth(withconditionssuchasduodenalatresia,omphaloceleordiaphragmatichernia)toyearsafterwardinconditionssuchaschronicmalrotationoftheintestine.
Traumaticcausesofanacuteabdomenrangefromstabandgunshotwoundstobluntabdominalinjuriesproducingsuchconditionsassplenicrupture.Historyorevidenceoftraumashouldmakethisdiagnosisfairlyobvious.
EXERCISE1OBJECTIVE1-Questions
1.Whatismeantbytheterm"
acuteabdomen?
"
2.Giveanexampleofanacuteabdomenduetoeachofthefollowingmechanisms:
∙a.Inflammation
∙b.Mechanicalobstruction
∙c.Vascularentities
EXERCISE1DISCUSSION
OBJECTIVE1Answers
1.Thetermreferstoacuteconditionsarisingwithintheabdomenassociatedwithsevereabdominalpain,requiringfairlyimmediatemanagementandoftenrequiringsurgery.
2.Oneexampleofeachis:
∙a.Acuteappendicitis
∙b.Incarceratedhernia
∙c.Mesentericarterialthrombosis.Ofcourse,therearemanyothers.
MINICOURSE2.4SECTION2
OBJ.2.Describethecauseandpathophysiologyofthefollowingacuteabdominaldiseases:
∙a.Acuteappendicitis-inflammatory
∙b.Acutesmallbowelobstructionmechanical
∙c.Mesentericvascularocclusion-vascular
∙d.Perforatedduodenalulcer-perforatedviscus
∙e.Peritonitis
CauseandPathophysiologyofAcuteAbdomen
a.AcuteAppendicitis
Inflammationintheappendixhasthesamefeaturesandfollowsthesamecourseasinflammationelsewhereinthegut.Itsimportanceisafunctionofitsfrequencyasaserioussurgicalconditionwithsignificantcomplications.
Obstructionoftheappendiceallumenbyfecalithswithinterferenceofthevascularsupplyareimportantfeaturesinitspathogenesis.Theessentialelementcausinginflammationofthewalloftheappendixisinvasionbybacteria.Theusualorganismsintheinflamedappendixarecolonbacilliandstreptococci,organismscommonlyfoundintheintestinaltract.Obstructionofthelumenandvascularocclusionprobablycontributebybreakingdowntheresistanceofthewalloftheappendixtoinvasionbypotentialpathogensinthegut.
Theearliestlesionisasuperficialulcerationofthemucosa.Spreadthenoccursfromthemucosatothemusclelayersandtheserosaandthelumenmaybecomefilledwithpus.Interferencewithcirculationleadstoareasofnecrosisandperforationoftheappendix,withspreadofinfectiontotheperitonealcavity.Iftheinfectionbecomeswalledoffaroundtheappendixalocalizedabscessmayresult.Otherwiseageneralizedperitonitisresults.
Thesamesortofinflammatoryprocessmayoccurinacutediverticulitiswhichusuallyinvolvesthedescendingandsigmoidcolon.Thisispromotedbythelodgingoffecalmaterialinadiverticulumwithspreadofinflammationtosurroundingtissue,andisaccompaniedbyleftlowerquadrantpain.
Inacutecholecystisthereisinflammationofthewallofthegallbladderduesochemicaldamagefromtheactionofconcentratedbile,promotedbyanobstructionofthecysticduct,usuallybystones.Bacterialinfectionwithstreptococciorcolonbacillimaysupervene.Inacutecholecystisthegallbladderislargeandhasathickedematouswall.Themucosashowsareasofulcerationandnecrosisandleukocytesarepresentinthewall.Pusmayfillthecavity,withanempyemaofthegallbladder.Necrosisandrupturemayoccur.
b.AcuteSmallBowelObstruction
Completeobstructiontothepassageofintestinalcontentiscausedeitherbymechanicalobstructionofthelumenorbyparalysisoftheintestinalmuscles(paralyticileus)andmaycausedeathinarelativelyshortperiodoftimeunlessrelieved.Acutemechanicalobstructionofthesmallboweliscausedmostcommonlyeitherbystrangulatedherniaorbyadhesionsandbands,usuallypost-operative,withtheperitonealcavity.
Agehasasignificantinfluenceonthecauseofsmallbowelobstruction.Innewborns,congenitalproblemssuchasatresiaofthegutareimportantcausesofobstructionandinsmallchildrenintussusceptionisencounteredwithfrequency.Theobstructionmaybeanentirelymechanicalocclusionofthelumen,whichisthecasewithanincarceratedhernia,congenitalatresiaofthelumenofthegut,andkinkingandexternalcompressionofthegutbyperitonealadhesions,usuallypost-operativeinorigin.
Theremay,however,beanassociatedinterferencewiththebloodandnervesupplyfortheintestines,inwhichcasethebowelissaidtobestrangulated.Obstructionsuchasanincarceratedhernia,ifnotpromptlyreduced,causesincreasingedemaofthegutwithimpairmentofthebloodsupply.Volvuluswithtwistingofthemesenteryandintussusception(whereonesegmentofthesmallbowelinvaginatesintoanother)alsocauseinterferencewithnerveandbloodsupply.Ischemicnecrosisorinfarctionofthebowelwalloccursunlessthebloodsupplyispromptlyrestored.Theinvolvedportionoftheintestinebecomesinturncongested,edematous,necroticandfinallygangrenous.Ingeneral,thehigherthesiteofanobstructionwithintheintestinaltract,themoreseverearetheassociatedsymptomsofexcessivevomitingwithdehydrationandchemicaldisturbancesoccurringbecauseofagreatlossofwaterandelectrolytes.
Themostcommoncauseoflowerintestinalobstructioniscarcinomaofthedistalportionofthecolon.Thedevelopmentoftheclinicalpictureisslowerthaninsmallbowelobstructionandpatientsdonotappearasillincomparablestages.Usuallytheacuteepisodeoflargebowelobstructionissuperimposedonprogressivechangeofbowelhabits,withdecreasingcaliberofthestoolsandincreasingconstipation.
Functionalintestinalobstructionduetoneurogenicfactorswhichcauseparalysisoftheintestinalmuscleandfailureofperistalsisisfairlycommon.Itistermedadynamicorparalyticileusanditoccurstosomeextentinmostpatientswhohaveundergoneabdomi
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