蔡锡渠宫颈癌筛查技术--HPV122检测.ppt
- 文档编号:18680686
- 上传时间:2023-09-07
- 格式:PPT
- 页数:1
- 大小:803.50KB
蔡锡渠宫颈癌筛查技术--HPV122检测.ppt
《蔡锡渠宫颈癌筛查技术--HPV122检测.ppt》由会员分享,可在线阅读,更多相关《蔡锡渠宫颈癌筛查技术--HPV122检测.ppt(1页珍藏版)》请在冰点文库上搜索。
这是一篇来自Khan的影响力非常大的文章,追踪了10年发现HPV18亚型,16亚型的比例最高Wehaveestablishedthesuperiorsensitivityofpooledhigh-riskHPV(hrHPV)DNAtestingcomparedwithcytologyindetectingcervicalprecancer.Nowletuslookatwhetheranyofthehigh-riskgenotypesaremorecarcinogenicthantheothers.InthisseminalHPVDNAstudybyKhanetal.,youcanseethatoveraperiodof10yearsoffollow-up,theriskofdevelopingCIN3orcancerissignificantlyhigherinwomenwithanHPV16orHPV18infectionatbaselinethaninthosewomenwithinfectionassociatedwithoneoftheother12high-riskHPVgenotypes.However,itisnoteworthythattheincidencerateofHPV18positivediseasewasslowertoaccumulatecomparedwiththeHPV16positivecumulativeincidencerate.GiventhepowerfulcarcinogenicpotentialofHPV16andHPV18itseemslogicaltoconsiderwhetherindividualdetectionofthesegenotypescouldbebeneficialforcervicalcancerprevention.Khanetal.lookedatdiseaseovertimeamongwomenwithnegativecytologywhotestedpositiveforHPVDNAatbaseline;colposcopywasperformedonceabnormalcytologyresultswereobserved.WhilethisstudydemonstratesthehigherdiseaseincidenceassociatedwithHPV16andHPV18,itisnotacompellingreasontotakeawomanwithapositiveHPV16orHPV18genotyperesultimmediatelytocolposcopy.TherewerenodataavailabletoinformphysiciansaboutdiseaseoutcomesforwomenmanagedusingthisscenariountilATHENA.
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 蔡锡渠 宫颈癌 技术 HPV122 检测